Development of Synthetic Detergents with Antiseptic Effect

Тетяна Сергіївна Тодосійчук


Influence of the main components of synthetic detergents on lytic activity of enzyme preparations of Cytorecifen and Cytorecifen-M was investigated in this work. On the basis of previously obtained results and the analysis of compositions of detergents the sodium carbonate, zeolite 4A, carboxymethylcellulose as well as superficially active substances synthanol and sulphanol were used. Lytic activity of the enzyme preparation and the powder synthetic washing means had been established by turbydimetric method by the ability of the lyses of Staphyloccus aureus 209 test-culture. As a result of the conducted research, lack of essential negative influence of the chosen components of detergents on lytic activity of studied enzyme preparations is established. There was development of two compositions of synthetic detergents with Cytorecifen maintenance and Cytorecifen-M, with the raised by 2–2,5 times antiseptic effect and for 8–10 % washing ability in relation to known means analogue. Powder Synthetic Detergent are proposed for the washing of textile regular products and industrial application (washing the hospital linen, etc.).


Synthetic detergent; Enzymes preparation; Lytic activity; Antiseptic effect; Composition


A.Vasconcelos et al., “Detergent Formulations for Wool Domestic Washings Containing Immobilized Enzymes,” Biotechn. Letters, vol. 28, is. 10, pp. 725–731, May 2006.

Chittoor Jabeena Thaz, Gurunathan Jayaraman, “Stability and Detergent Compatibility of a Predominantly β-Sheet Serine Protease from Halotolerant B. aquimaris VITP4 Strain”, Appl. Biochem. and Biotech., vol. 172, is. 2, pp. 687–700, January 2014.

H.S. Olsen, P. Falholt, “The role of enzymes in modern detergency,” J. of Surfactants and Detergents, vol.1, is. 4, pp. 555–567, Oct. 1998.

E.V. Kudryashova et al., “Stabilization of alkaline prote­inase and cellulases via complex formation with chitosan for use as detergent components,” Rus. Journ. of Bioorg. Chem., vol. 35, is. 3, pp. 335–341, May 2009.

Izuddin Abdul Rahman et al., “Formulation and Evalua­tion of an Automatic Dishwashing Detergent Containing T1 Lipase”, J. of Surfactants and Detergents, vol. 16, is. 3, pp. 427–434 , May 2013.

Madhura Nerurkar et al., “Application of Lipase from Marine Bacteria Bacillus sonorensis as an Additive in Detergent Formulation”, J. of Surfactants and Detergents, vol. 16, is. 3, pp. 435–443, May 2013.

Тодосійчук Т.С. Розробка технології гідролітичного ферментного препарату Циторецифен: Автореф. дис. … канд. техн. наук. – К., 2000. – 26 с.

Покас О.В., Поліщук О.І., Тодосійчук Т.С. Дія фермент­ного препарату “Циторецифен-М” на здатність до утворення біоплівок штамами Pseudomonas aeruginosa // Проф. медицина. – 2011. – №2 (14). – С. 81–85.

Шинкаренко Л.М., Тодосійчук Т.С., Хоккер Х. Дослідження компонентного складу і специфічності літичного ферментного комплексу Streptomyces recifensis var. lyticus IMB Ac-5001 // Наук. вісті НТУУ “КПІ”. – 2004. – № 1. – С. 138–143.

Тодосійчук Т.С., Будько М.О. Аспекти немедичного застосування препаратів бактеріолізинів стрептоміцетів // Наук. пр. НУХТ. – 2012. – № 43. – C. 32–37.

Патент України на корисну модель, МПК С 11 D 1/00, С 11 D 3/04. Порошкоподібний синтетичний мийний засіб з антисептичним ефектом / Тодосійчук Т.С., Іздебська Т.І.; патентовл. НТУУ “КПІ”. – № 83258; Заявл. 11.04.2013, Опубл. 27.08.2013, Бюл. № 16.

GOST Style Citations



  • There are currently no refbacks.

Copyright (c) 2017 NTUU KPI